Images supplied by the South African Medical Research Council

It was all about teamwork and scaling up international collaborations as leading University of the Western Cape (UWC) scholar Professor Alan Christoffels' "outstanding contribution" to science earned him a top national award.


Prof Christoffels won the prestigious Gold Scientific Achievement Award at the 2023 South African Medical Research Council Merit Awards in Parow last night (7 March 2024). 
 
The awards recognise individuals who have demonstrated exceptional scientific acumen and have made innovative strides in addressing public health challenges, potentially influencing policy and enhancing the well-being of the South African population. 
 
The gold medals are reserved for accomplished senior scientists who have made seminal contributions that have profoundly impacted people's health, particularly those residing in developing nations.

This award comes with a Gold Medal and a R30 000 cash prize to the primary organisation he is affiliated with.
 
"It feels good that all my students and staff who worked with me over the years are recognised. The success of the research was not possible without the postgraduate students and researchers whom I work with," Prof Christoffels said after receiving the award.

"This recognition echoes the impact of the work we do at UWC. It shows that others value the knowledge that we have contributed to the field".
 
He could not pinpoint specific projects that have earned him the recognition but noted that the theme in all that they do in his team is analysing genomic data and building methods to assist in analysing that data. "We have been consistent and intentional about partnering with national and global players to maximise the impact of our work. It was also possible to scale up our efforts by joining forces with others".
 
Over the past 15 years, Prof Christoffels has managed a successful South African national research chair in Bioinformatics and Health Genomics to deepen the integration of bioinformatics - using computational tools to interpret biological data - into public health. 
 
His research team has earned international acclaim for developing methods to analyse next-generation sequencing data. For instance, in the context of infectious diseases, he has worked on genomic variants of multidrug-resistant tuberculosis through projects such as COMBAT-TB. 
 
Prof Christoffels and SANBI have also taken leading roles in the field of pathogen genomics on the continent. In 2018, he supported the Africa Centre for Disease Control and Prevention (Africa CDC), the public health agency of the African Union, in the development of an Africa-wide plan for strengthening disease surveillance using genomic sequencing. Following this foundational work, Africa CDC in 2020 launched the African Pathogen Genomics Initiative, a US$100-million, four-year partnership to expand access to next-generation genomic sequencing tools and expertise in Africa.
 
Prof Christoffels, who is also the director of the South African National Bioinformatics Institute and of the SAMRC Bioinformatics Unit, has some wise words for the next generations of researchers.

"The reality is that research costs money, and research funding attracts more funding. Identifying strategic partnerships is helpful because these projects help us to build a coherent body of work that, in turn, provides the entry point to further research project funding. International collaboration is key. We learn from one another, and the next generation of scientists must remember that they, too, have lots to offer for multinational projects. We sometimes feel intimidated when we start out but are equal partners in any scientific collaboration".

Click here to watch the SAMRC honor Gold Award recipient Professor Alan Christoffels